High Throughput Sequencing Platform

The High Throughput Sequencing Platform represents an advanced and comprehensive technology platofrm that encompasses the entire workflow from nucleic acid extraction, library preparation to next-generation sequencing. This platform is capable of analyzing DNA and RNA from a wide range of biological samples, including blood, fresh tissues, cells, FFPE specimens, viruses, bacteria, and other microorganisms. It employs a variety of library construction strategies such as WGS, WGBS, ATAC-seq, ChIP-seq, RNA-seq, CUT&Tag, among others, supporting applications in tumor early detection, mutation analysis, genetic testing, prenatal screening, pathogen identification, and related research areas.

Functionality of the platform includes:

1. Extraction of nucleic acids from diverse biological samples, including cells, tissues, blood, and viruses.

2. Fragmentation of cells, proteins, chromatin, and nucleic acids.

3. Analysis of protein profiles, DNA and RNA fragment distributions.

4. Quantification of nucleic acids using both absolute (Qubit) and relative (real-time fluorescence) methods.

5. Sequencing of libraries generated by platforms such as MGI and Illumina, as well as specialized structured libraries.

6. Construction of next-generation sequencing (NGS) libraries for various applications including WGS, WGBS, RNA-seq, EM-Seq, ChIP-seq, ATAC-seq, CUT&Tag, etc.